The church and attached hospital served as a hospital from 1516-1816. From 1816-1961 it served as a maternity hospital and foundling home. In 1980 it was taken over by the city for exhibitions and the tourism office, as it sits opposite the Great Mosque (where Hernan Ruiz I also worked on the interior alterations). The core of the historic building are the cloisters of Moorish influence and the chapel of flamboyant Gothic style rich in Plateresque decoration, the work of Hernan Ruiz I, who also made main portico in 1514.